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Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy
Autophagy is a major pathway for the clearance of harmful material from the cytoplasm. During autophagy, cytoplasmic material is delivered into the lysosomal system by organelles called autophagosomes. Autophagosomes form in a de novo manner and, in the course of their formation, isolate cargo mater...
Autores principales: | Wurzer, Bettina, Zaffagnini, Gabriele, Fracchiolla, Dorotea, Turco, Eleonora, Abert, Christine, Romanov, Julia, Martens, Sascha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684078/ https://www.ncbi.nlm.nih.gov/pubmed/26413874 http://dx.doi.org/10.7554/eLife.08941 |
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