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High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED
Profiling microbial community function from metagenomic sequencing data remains a computationally challenging problem. Mapping millions of DNA reads from such samples to reference protein databases requires long run-times, and short read lengths can result in spurious hits to unrelated proteins (los...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684307/ https://www.ncbi.nlm.nih.gov/pubmed/26682918 http://dx.doi.org/10.1371/journal.pcbi.1004557 |