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EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes

Epithelial renewal in the Drosophila intestine is orchestrated by Intestinal Stem Cells (ISCs). Following damage or stress the intestinal epithelium produces ligands that activate the epidermal growth factor receptor (EGFR) in ISCs. This promotes their growth and division and, thereby, epithelial re...

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Detalles Bibliográficos
Autores principales: Jin, Yinhua, Ha, Nati, Forés, Marta, Xiang, Jinyi, Gläßer, Christine, Maldera, Julieta, Jiménez, Gerardo, Edgar, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684324/
https://www.ncbi.nlm.nih.gov/pubmed/26683696
http://dx.doi.org/10.1371/journal.pgen.1005634

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