Genome Wide Methylome Alterations in Lung Cancer

Aberrant cytosine 5-methylation underlies many deregulated elements of cancer. Among paired non-small cell lung cancers (NSCLC), we sought to profile DNA 5-methyl-cytosine features which may underlie genome-wide deregulation. In one of the more dense interrogations of the methylome, we sampled 1.2 m...

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Detalles Bibliográficos
Autores principales: Mullapudi, Nandita, Ye, Bin, Suzuki, Masako, Fazzari, Melissa, Han, Weiguo, Shi, Miao K., Marquardt, Gaby, Lin, Juan, Wang, Tao, Keller, Steven, Zhu, Changcheng, Locker, Joseph D., Spivack, Simon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684329/
https://www.ncbi.nlm.nih.gov/pubmed/26683690
http://dx.doi.org/10.1371/journal.pone.0143826

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