Establishment of an Animal Model of Bisphosphonate-Related Osteonecrosis of the Jaws in Spontaneously Diabetic Torii Rats

BACKGROUND: We evaluated the side effects of bisphosphonate (BP) on tooth extraction socket healing in spontaneously diabetic Torii (SDT) rats, an established model of non-obese type 2 diabetes mellitus, to develop an animal model of BP-related osteonecrosis of the jaws (BRONJ). MATERIALS AND METHOD...

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Detalles Bibliográficos
Autores principales: Takaoka, Kazuki, Yamamura, Michiyo, Nishioka, Toshihiro, Abe, Tetsuya, Tamaoka, Joji, Segawa, Emi, Shinohara, Masami, Ueda, Haruyasu, Kishimoto, Hiromitsu, Urade, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684366/
https://www.ncbi.nlm.nih.gov/pubmed/26659123
http://dx.doi.org/10.1371/journal.pone.0144355

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