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Iron Chelators and Antioxidants Regenerate Neuritic Tree and Nigrostriatal Fibers of MPP+/MPTP-Lesioned Dopaminergic Neurons
Neuronal death in Parkinson’s disease (PD) is often preceded by axodendritic tree retraction and loss of neuronal functionality. The presence of non-functional but live neurons opens therapeutic possibilities to recover functionality before clinical symptoms develop. Considering that iron accumulati...
Autores principales: | Aguirre, Pabla, Mena, Natalia P., Carrasco, Carlos M., Muñoz, Yorka, Pérez-Henríquez, Patricio, Morales, Rodrigo A., Cassels, Bruce K., Méndez-Gálvez, Carolina, García-Beltrán, Olimpo, González-Billault, Christian, Núñez, Marco T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684383/ https://www.ncbi.nlm.nih.gov/pubmed/26658949 http://dx.doi.org/10.1371/journal.pone.0144848 |
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