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Rhubarb Enema Attenuates Renal Tubulointerstitial Fibrosis in 5/6 Nephrectomized Rats by Alleviating Indoxyl Sulfate Overload
AIM: To investigate the effects of rhubarb enema treatment using a 5/6 nephrectomized rat model and study its mechanisms. METHODS: Twenty-eight Sprague Dawley rats were divided into three groups: sham operation group (n = 8), 5/6 nephrectomized (5/6Nx) (n = 10), and 5/6Nx with rhubarb enema treatmen...
Autores principales: | Lu, Zhaoyu, Zeng, Yuqun, Lu, Fuhua, Liu, Xusheng, Zou, Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684395/ https://www.ncbi.nlm.nih.gov/pubmed/26671452 http://dx.doi.org/10.1371/journal.pone.0144726 |
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