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Rhubarb Enema Attenuates Renal Tubulointerstitial Fibrosis in 5/6 Nephrectomized Rats by Alleviating Indoxyl Sulfate Overload

AIM: To investigate the effects of rhubarb enema treatment using a 5/6 nephrectomized rat model and study its mechanisms. METHODS: Twenty-eight Sprague Dawley rats were divided into three groups: sham operation group (n = 8), 5/6 nephrectomized (5/6Nx) (n = 10), and 5/6Nx with rhubarb enema treatmen...

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Detalles Bibliográficos
Autores principales: Lu, Zhaoyu, Zeng, Yuqun, Lu, Fuhua, Liu, Xusheng, Zou, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684395/
https://www.ncbi.nlm.nih.gov/pubmed/26671452
http://dx.doi.org/10.1371/journal.pone.0144726

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