The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress

Dopamine is a neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dysfunction of the dopamine system has been implicated in different nervous system diseases. The level of dopamine transmission increases in response to any type of reward...

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Detalles Bibliográficos
Autores principales: Juárez Olguín, Hugo, Calderón Guzmán, David, Hernández García, Ernestina, Barragán Mejía, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684895/
https://www.ncbi.nlm.nih.gov/pubmed/26770661
http://dx.doi.org/10.1155/2016/9730467
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author Juárez Olguín, Hugo
Calderón Guzmán, David
Hernández García, Ernestina
Barragán Mejía, Gerardo
author_facet Juárez Olguín, Hugo
Calderón Guzmán, David
Hernández García, Ernestina
Barragán Mejía, Gerardo
author_sort Juárez Olguín, Hugo
collection PubMed
description Dopamine is a neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dysfunction of the dopamine system has been implicated in different nervous system diseases. The level of dopamine transmission increases in response to any type of reward and by a large number of strongly additive drugs. The role of dopamine dysfunction as a consequence of oxidative stress is involved in health and disease. Introduce new potential targets for the development of therapeutic interventions based on antioxidant compounds. The present review focuses on the therapeutic potential of antioxidant compounds as a coadjuvant treatment to conventional neurological disorders is discussed.
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spelling pubmed-46848952016-01-14 The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress Juárez Olguín, Hugo Calderón Guzmán, David Hernández García, Ernestina Barragán Mejía, Gerardo Oxid Med Cell Longev Review Article Dopamine is a neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dysfunction of the dopamine system has been implicated in different nervous system diseases. The level of dopamine transmission increases in response to any type of reward and by a large number of strongly additive drugs. The role of dopamine dysfunction as a consequence of oxidative stress is involved in health and disease. Introduce new potential targets for the development of therapeutic interventions based on antioxidant compounds. The present review focuses on the therapeutic potential of antioxidant compounds as a coadjuvant treatment to conventional neurological disorders is discussed. Hindawi Publishing Corporation 2016 2015-12-06 /pmc/articles/PMC4684895/ /pubmed/26770661 http://dx.doi.org/10.1155/2016/9730467 Text en Copyright © 2016 Hugo Juárez Olguín et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Juárez Olguín, Hugo
Calderón Guzmán, David
Hernández García, Ernestina
Barragán Mejía, Gerardo
The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress
title The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress
title_full The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress
title_fullStr The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress
title_full_unstemmed The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress
title_short The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress
title_sort role of dopamine and its dysfunction as a consequence of oxidative stress
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684895/
https://www.ncbi.nlm.nih.gov/pubmed/26770661
http://dx.doi.org/10.1155/2016/9730467
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