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Prevalence of Torque teno virus in healthy donors of Paraná State, southern Brazil

OBJECTIVE: To determine the prevalence of the Torque teno virus in healthy donors in the northern and northwestern regions of the state of Paraná, southern Brazil. METHODS: The Torque teno virus was detected by a nested polymerase chain reaction using a set of oligoprimers for the N22 region. RESULT...

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Autores principales: Mazzola, Jocimara Costa, Saito, Patrícia Keiko, Yamakawa, Roger Haruki, Watanabe, Maria Angélica Ehara, da Silva Junior, Waldir Veríssimo, Matta, Alessandra Cristina Gobbi, Borelli, Sueli Donizete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685100/
https://www.ncbi.nlm.nih.gov/pubmed/26408369
http://dx.doi.org/10.1016/j.bjhh.2015.07.005
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author Mazzola, Jocimara Costa
Saito, Patrícia Keiko
Yamakawa, Roger Haruki
Watanabe, Maria Angélica Ehara
da Silva Junior, Waldir Veríssimo
Matta, Alessandra Cristina Gobbi
Borelli, Sueli Donizete
author_facet Mazzola, Jocimara Costa
Saito, Patrícia Keiko
Yamakawa, Roger Haruki
Watanabe, Maria Angélica Ehara
da Silva Junior, Waldir Veríssimo
Matta, Alessandra Cristina Gobbi
Borelli, Sueli Donizete
author_sort Mazzola, Jocimara Costa
collection PubMed
description OBJECTIVE: To determine the prevalence of the Torque teno virus in healthy donors in the northern and northwestern regions of the state of Paraná, southern Brazil. METHODS: The Torque teno virus was detected by a nested polymerase chain reaction using a set of oligoprimers for the N22 region. RESULTS: The prevalence of the virus was 69% in 551 healthy blood donors in southern Brazil. There was no statistically significant difference between the presence of the virus and the variables gender, ethnicity and marital status. There was significant difference in the prevalence of the virus regarding the age of the donors (p-value = 0.024) with a higher incidence (74.7%) in 18- to 24-year-old donors. CONCLUSION: A high prevalence of Torque teno virus was observed in the population studied. Further studies are needed to elucidate the routes of contamination and the clinical implications of the virus in the healthy population.
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spelling pubmed-46851002016-01-15 Prevalence of Torque teno virus in healthy donors of Paraná State, southern Brazil Mazzola, Jocimara Costa Saito, Patrícia Keiko Yamakawa, Roger Haruki Watanabe, Maria Angélica Ehara da Silva Junior, Waldir Veríssimo Matta, Alessandra Cristina Gobbi Borelli, Sueli Donizete Rev Bras Hematol Hemoter Original Article OBJECTIVE: To determine the prevalence of the Torque teno virus in healthy donors in the northern and northwestern regions of the state of Paraná, southern Brazil. METHODS: The Torque teno virus was detected by a nested polymerase chain reaction using a set of oligoprimers for the N22 region. RESULTS: The prevalence of the virus was 69% in 551 healthy blood donors in southern Brazil. There was no statistically significant difference between the presence of the virus and the variables gender, ethnicity and marital status. There was significant difference in the prevalence of the virus regarding the age of the donors (p-value = 0.024) with a higher incidence (74.7%) in 18- to 24-year-old donors. CONCLUSION: A high prevalence of Torque teno virus was observed in the population studied. Further studies are needed to elucidate the routes of contamination and the clinical implications of the virus in the healthy population. Sociedade Brasileira de Hematologia e Hemoterapia 2015 2015-07-29 /pmc/articles/PMC4685100/ /pubmed/26408369 http://dx.doi.org/10.1016/j.bjhh.2015.07.005 Text en © 2015 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. Published by Elsevier Editora Ltda. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Mazzola, Jocimara Costa
Saito, Patrícia Keiko
Yamakawa, Roger Haruki
Watanabe, Maria Angélica Ehara
da Silva Junior, Waldir Veríssimo
Matta, Alessandra Cristina Gobbi
Borelli, Sueli Donizete
Prevalence of Torque teno virus in healthy donors of Paraná State, southern Brazil
title Prevalence of Torque teno virus in healthy donors of Paraná State, southern Brazil
title_full Prevalence of Torque teno virus in healthy donors of Paraná State, southern Brazil
title_fullStr Prevalence of Torque teno virus in healthy donors of Paraná State, southern Brazil
title_full_unstemmed Prevalence of Torque teno virus in healthy donors of Paraná State, southern Brazil
title_short Prevalence of Torque teno virus in healthy donors of Paraná State, southern Brazil
title_sort prevalence of torque teno virus in healthy donors of paraná state, southern brazil
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685100/
https://www.ncbi.nlm.nih.gov/pubmed/26408369
http://dx.doi.org/10.1016/j.bjhh.2015.07.005
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