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Fuyuan Decoction Enhances SOX9 and COL2A1 Expression and Smad2/3 Phosphorylation in IL-1β-Activated Chondrocytes

Fuyuan Decoction (FYD), a herbal formula in China, has been widely used for osteoarthritis (OA) treatment. Herein, we determined the effects of FYD on the expression of transcription factor SOX9 and its target gene collagen type II, alpha 1 (COL2A1) as well as the activation of Smad2/3 in interleuki...

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Detalles Bibliográficos
Autores principales: Zhang, Yudi, Li, Rongheng, Zhong, Yu, Zhang, Sihan, Zhou, Lingyun, Shang, Shike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685114/
https://www.ncbi.nlm.nih.gov/pubmed/26770254
http://dx.doi.org/10.1155/2015/821947