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A rare case of fibrostenotic endobronchial tuberculosis of trachea

Endobronchial tuberculosis (EBTB) is a sequelae of pulmonary tuberculosis (TB) that extends to the endobronchial or endotracheal wall causing inflammation, edema, ulceration, granulation or fibrosis of mucosa and submucosa. This case depicts a 20 year old foreign-born woman with a history of active...

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Autores principales: Cary, Cassiopia, Jhajj, Manjit, Cinicola, John, Evans, Richard, Cheriyath, Pramil, Gorepatti, Venaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685201/
https://www.ncbi.nlm.nih.gov/pubmed/26779339
http://dx.doi.org/10.1016/j.amsu.2015.10.007
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author Cary, Cassiopia
Jhajj, Manjit
Cinicola, John
Evans, Richard
Cheriyath, Pramil
Gorepatti, Venaka
author_facet Cary, Cassiopia
Jhajj, Manjit
Cinicola, John
Evans, Richard
Cheriyath, Pramil
Gorepatti, Venaka
author_sort Cary, Cassiopia
collection PubMed
description Endobronchial tuberculosis (EBTB) is a sequelae of pulmonary tuberculosis (TB) that extends to the endobronchial or endotracheal wall causing inflammation, edema, ulceration, granulation or fibrosis of mucosa and submucosa. This case depicts a 20 year old foreign-born woman with a history of active pulmonary TB on anti-TB chemotherapy, who presented with worsening stridor, dyspnea, cough and weight loss. The disease state was diagnosed with multiple modalities including, spirometry, CT scan of the neck, and bronchoscopy. The biopsies of the tracheal web revealed fibrotic tissue without any granulomas or malignancy establishing the diagnosis of EBTB. Serial balloon dilations and anti-neoplastic therapy with Mitomycin C was used to accomplish sufficient airway patency to relieve her symptoms. ETBT is a rare consequence of TB, which although has a low incidence in the United States, so physicians should have a high clinical suspicion based on the need for prompt intervention.
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spelling pubmed-46852012016-01-15 A rare case of fibrostenotic endobronchial tuberculosis of trachea Cary, Cassiopia Jhajj, Manjit Cinicola, John Evans, Richard Cheriyath, Pramil Gorepatti, Venaka Ann Med Surg (Lond) Case Report Endobronchial tuberculosis (EBTB) is a sequelae of pulmonary tuberculosis (TB) that extends to the endobronchial or endotracheal wall causing inflammation, edema, ulceration, granulation or fibrosis of mucosa and submucosa. This case depicts a 20 year old foreign-born woman with a history of active pulmonary TB on anti-TB chemotherapy, who presented with worsening stridor, dyspnea, cough and weight loss. The disease state was diagnosed with multiple modalities including, spirometry, CT scan of the neck, and bronchoscopy. The biopsies of the tracheal web revealed fibrotic tissue without any granulomas or malignancy establishing the diagnosis of EBTB. Serial balloon dilations and anti-neoplastic therapy with Mitomycin C was used to accomplish sufficient airway patency to relieve her symptoms. ETBT is a rare consequence of TB, which although has a low incidence in the United States, so physicians should have a high clinical suspicion based on the need for prompt intervention. Elsevier 2015-10-22 /pmc/articles/PMC4685201/ /pubmed/26779339 http://dx.doi.org/10.1016/j.amsu.2015.10.007 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Cary, Cassiopia
Jhajj, Manjit
Cinicola, John
Evans, Richard
Cheriyath, Pramil
Gorepatti, Venaka
A rare case of fibrostenotic endobronchial tuberculosis of trachea
title A rare case of fibrostenotic endobronchial tuberculosis of trachea
title_full A rare case of fibrostenotic endobronchial tuberculosis of trachea
title_fullStr A rare case of fibrostenotic endobronchial tuberculosis of trachea
title_full_unstemmed A rare case of fibrostenotic endobronchial tuberculosis of trachea
title_short A rare case of fibrostenotic endobronchial tuberculosis of trachea
title_sort rare case of fibrostenotic endobronchial tuberculosis of trachea
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685201/
https://www.ncbi.nlm.nih.gov/pubmed/26779339
http://dx.doi.org/10.1016/j.amsu.2015.10.007
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