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Thrombopoietin induces production of nucleated thrombocytes from liver cells in Xenopus laevis

The development of mammalian megakaryocytes (MKs) and platelets, which are thought to be absent in non-mammals, is primarily regulated by the thrombopoietin (TPO)/Mpl system. Although non-mammals possess nucleated thrombocytes instead of platelets, the features of nucleated thrombocyte progenitors r...

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Detalles Bibliográficos
Autores principales: Tanizaki, Yuta, Ichisugi, Megumi, Obuchi-Shimoji, Miyako, Ishida-Iwata, Takako, Tahara-Mogi, Ayaka, Meguro-Ishikawa, Mizue, Kato, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685256/
https://www.ncbi.nlm.nih.gov/pubmed/26687619
http://dx.doi.org/10.1038/srep18519