Microvesicle phenotypes are associated with transfusion requirements and mortality in subjects with severe injuries

BACKGROUND: Severe injury often results in substantial bleeding and mortality. Injury provokes cellular activation and release of extracellular vesicles. Circulating microvesicles (MVs) are predominantly platelet-derived and highly procoagulant. They support hemostasis and vascular function. The rol...

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Detalles Bibliográficos
Autores principales: Matijevic, Nena, Wang, Yao-Wei W., Holcomb, John B., Kozar, Rosemary, Cardenas, Jessica C., Wade, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2015
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685295/
https://www.ncbi.nlm.nih.gov/pubmed/26689982
http://dx.doi.org/10.3402/jev.v4.29338

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