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Risk Factors for Survival following Open Surgical Repair of Ruptured Abdominal Aortic Aneurysms: A 13-Year Experience

Background: Surgical treatment of a ruptured abdominal aorta aneurysm (RAAA) continues to present a significant challenge to surgeons. There are some patient factors such as age and gender that cannot be changed, and comorbid conditions can be optimized but not eliminated. The purpose of this study...

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Autores principales: Ozen, Anil, Hanedan, Muhammet Onur, Songur, Çetin Murat, Boysan, Emre, Unal, Ertekin Utku, Mola, Serkan, Erkengel, Halil Ibrahim, Kubat, Emre, Iscan, Zafer, Tutun, Ufuk, Sarıtas, Ahmet, Birincioglu, Cemal Levent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences, 2006- 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685366/
https://www.ncbi.nlm.nih.gov/pubmed/26697083
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author Ozen, Anil
Hanedan, Muhammet Onur
Songur, Çetin Murat
Boysan, Emre
Unal, Ertekin Utku
Mola, Serkan
Erkengel, Halil Ibrahim
Kubat, Emre
Iscan, Zafer
Tutun, Ufuk
Sarıtas, Ahmet
Birincioglu, Cemal Levent
author_facet Ozen, Anil
Hanedan, Muhammet Onur
Songur, Çetin Murat
Boysan, Emre
Unal, Ertekin Utku
Mola, Serkan
Erkengel, Halil Ibrahim
Kubat, Emre
Iscan, Zafer
Tutun, Ufuk
Sarıtas, Ahmet
Birincioglu, Cemal Levent
author_sort Ozen, Anil
collection PubMed
description Background: Surgical treatment of a ruptured abdominal aorta aneurysm (RAAA) continues to present a significant challenge to surgeons. There are some patient factors such as age and gender that cannot be changed, and comorbid conditions can be optimized but not eliminated. The purpose of this study was to identify the risk factors affecting high mortality after the surgical repair of an RAAA. Methods: Data on 121 patients who underwent surgical repair for RAAAs between January 1997 and June 2011 in our institution were collected retrospectively. All the patients had been diagnosed by computed tomography (CT) scans, and intraoperative extra-luminal blood was visualized intraoperatively. Variables studied comprised demographic data; preoperative, operative, and postoperative data; and the causes of mortality. Multivariate regression analysis was used to determine the predictors of mortality. Results: One hundred eight (89.2%) patients were male and 13 (10.7%) were female at an average age of 68.9 ± 10.5 years. Totally, 121 patients underwent surgery for RAAAs. Fifty-four patients had aortic tube grafts, 32 aortobiiliac grafts, 20 aortobifemoral grafts, 1 aortoiliac graft, and 1 aortofemoral graft for the replacement of the RAAAs. Seven patients had only surgical exploration. Operative mortality was 41.3% (50 patients). The factors associated with mortality were preoperative shock, free blood, positive inotropic agent, hematocrit value, and need for blood and plasma. In the multivariate analysis, preoperative shock and positive inotropic agents were found to be significant as the predictors of death (OR: 19.8, 95%CI: 3.2-122.8 and OR: 8.6, 95% CI: 2.9-26.3, respectively). Conclusion: This study revealed that the preoperative clinical findings affected the mortality associated with RAAAs.
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spelling pubmed-46853662015-12-22 Risk Factors for Survival following Open Surgical Repair of Ruptured Abdominal Aortic Aneurysms: A 13-Year Experience Ozen, Anil Hanedan, Muhammet Onur Songur, Çetin Murat Boysan, Emre Unal, Ertekin Utku Mola, Serkan Erkengel, Halil Ibrahim Kubat, Emre Iscan, Zafer Tutun, Ufuk Sarıtas, Ahmet Birincioglu, Cemal Levent J Tehran Heart Cent Original Article Background: Surgical treatment of a ruptured abdominal aorta aneurysm (RAAA) continues to present a significant challenge to surgeons. There are some patient factors such as age and gender that cannot be changed, and comorbid conditions can be optimized but not eliminated. The purpose of this study was to identify the risk factors affecting high mortality after the surgical repair of an RAAA. Methods: Data on 121 patients who underwent surgical repair for RAAAs between January 1997 and June 2011 in our institution were collected retrospectively. All the patients had been diagnosed by computed tomography (CT) scans, and intraoperative extra-luminal blood was visualized intraoperatively. Variables studied comprised demographic data; preoperative, operative, and postoperative data; and the causes of mortality. Multivariate regression analysis was used to determine the predictors of mortality. Results: One hundred eight (89.2%) patients were male and 13 (10.7%) were female at an average age of 68.9 ± 10.5 years. Totally, 121 patients underwent surgery for RAAAs. Fifty-four patients had aortic tube grafts, 32 aortobiiliac grafts, 20 aortobifemoral grafts, 1 aortoiliac graft, and 1 aortofemoral graft for the replacement of the RAAAs. Seven patients had only surgical exploration. Operative mortality was 41.3% (50 patients). The factors associated with mortality were preoperative shock, free blood, positive inotropic agent, hematocrit value, and need for blood and plasma. In the multivariate analysis, preoperative shock and positive inotropic agents were found to be significant as the predictors of death (OR: 19.8, 95%CI: 3.2-122.8 and OR: 8.6, 95% CI: 2.9-26.3, respectively). Conclusion: This study revealed that the preoperative clinical findings affected the mortality associated with RAAAs. Tehran University of Medical Sciences, 2006- 2015-07-03 /pmc/articles/PMC4685366/ /pubmed/26697083 Text en Copyright © 2015 Tehran Heart Center, Tehran University of Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ozen, Anil
Hanedan, Muhammet Onur
Songur, Çetin Murat
Boysan, Emre
Unal, Ertekin Utku
Mola, Serkan
Erkengel, Halil Ibrahim
Kubat, Emre
Iscan, Zafer
Tutun, Ufuk
Sarıtas, Ahmet
Birincioglu, Cemal Levent
Risk Factors for Survival following Open Surgical Repair of Ruptured Abdominal Aortic Aneurysms: A 13-Year Experience
title Risk Factors for Survival following Open Surgical Repair of Ruptured Abdominal Aortic Aneurysms: A 13-Year Experience
title_full Risk Factors for Survival following Open Surgical Repair of Ruptured Abdominal Aortic Aneurysms: A 13-Year Experience
title_fullStr Risk Factors for Survival following Open Surgical Repair of Ruptured Abdominal Aortic Aneurysms: A 13-Year Experience
title_full_unstemmed Risk Factors for Survival following Open Surgical Repair of Ruptured Abdominal Aortic Aneurysms: A 13-Year Experience
title_short Risk Factors for Survival following Open Surgical Repair of Ruptured Abdominal Aortic Aneurysms: A 13-Year Experience
title_sort risk factors for survival following open surgical repair of ruptured abdominal aortic aneurysms: a 13-year experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685366/
https://www.ncbi.nlm.nih.gov/pubmed/26697083
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