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Crystal Structure of Human SSRP1 Middle Domain Reveals a Role in DNA Binding

SSRP1 is a subunit of the FACT complex, an important histone chaperone required for transcriptional regulation, DNA replication and damage repair. SSRP1 also plays important roles in transcriptional regulation independent of Spt16 and interacts with other proteins. Here, we report the crystal struct...

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Detalles Bibliográficos
Autores principales:	Zhang, Wenjuan, Zeng, Fuxing, Liu, Yiwei, Shao, Chen, Li, Sai, Lv, Hui, Shi, Yunyu, Niu, Liwen, Teng, Maikun, Li, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685450/ https://www.ncbi.nlm.nih.gov/pubmed/26687053 http://dx.doi.org/10.1038/srep18688

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