Genetic disruption of Ano5 in mice does not recapitulate human ANO5-deficient muscular dystrophy

BACKGROUND: Anoctamin 5 (ANO5) is a member of a conserved gene family (TMEM16), which codes for proteins predicted to have eight transmembrane domains and putative Ca(2+)-activated chloride channel (CaCC) activity. It was recently reported that mutations in this gene result in the development of lim...

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Detalles Bibliográficos
Autores principales: Xu, Jing, El Refaey, Mona, Xu, Li, Zhao, Lixia, Gao, Yandi, Floyd, Kyle, Karaze, Tallib, Janssen, Paul M. L., Han, Renzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685631/
https://www.ncbi.nlm.nih.gov/pubmed/26693275
http://dx.doi.org/10.1186/s13395-015-0069-z

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