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Testing gene therapy vectors in human primary nasal epithelial cultures

Cystic fibrosis (CF) results from mutations in the CF transmembrane conductance regulator (CFTR) gene, which codes for a chloride/bicarbonate channel in the apical epithelial membranes. CFTR dysfunction results in a multisystem disease including the development of life limiting lung disease. The pos...

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Detalles Bibliográficos
Autores principales: Cao, Huibi, Ouyang, Hong, Ip, Wan, Du, Kai, Duan, Wenming, Avolio, Julie, Wu, Jing, Duan, Cathleen, Yeger, Herman, Bear, Christine E, Gonska, Tanja, Hu, Jim, Moraes, Theo J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685663/
https://www.ncbi.nlm.nih.gov/pubmed/26730394
http://dx.doi.org/10.1038/mtm.2015.34