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Testing gene therapy vectors in human primary nasal epithelial cultures
Cystic fibrosis (CF) results from mutations in the CF transmembrane conductance regulator (CFTR) gene, which codes for a chloride/bicarbonate channel in the apical epithelial membranes. CFTR dysfunction results in a multisystem disease including the development of life limiting lung disease. The pos...
Autores principales: | Cao, Huibi, Ouyang, Hong, Ip, Wan, Du, Kai, Duan, Wenming, Avolio, Julie, Wu, Jing, Duan, Cathleen, Yeger, Herman, Bear, Christine E, Gonska, Tanja, Hu, Jim, Moraes, Theo J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685663/ https://www.ncbi.nlm.nih.gov/pubmed/26730394 http://dx.doi.org/10.1038/mtm.2015.34 |
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