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Insights into Hydrate Formation and Stability of Morphinanes from a Combination of Experimental and Computational Approaches
[Image: see text] Morphine, codeine, and ethylmorphine are important drug compounds whose free bases and hydrochloride salts form stable hydrates. These compounds were used to systematically investigate the influence of the type of functional groups, the role of water molecules, and the Cl(–) counte...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685752/ https://www.ncbi.nlm.nih.gov/pubmed/25036525 http://dx.doi.org/10.1021/mp500334z |