Organocatalytic and enantioselective Michael reaction between α-nitroesters and nitroalkenes. Syn/anti-selectivity control using catalysts with the same absolute backbone chirality

The asymmetric and catalytic Michael reaction between α-nitroesters and nitroalkenes has been studied in the presence of two bifunctional catalysts both containing the same absolute chirality at the carbon backbone. The reaction performed in similar conditions allows us to control the syn or anti se...

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Autores principales: Martínez, Jose I, Uria, Uxue, Muñiz, Maria, Reyes, Efraím, Carrillo, Luisa, Vicario, Jose L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685793/
https://www.ncbi.nlm.nih.gov/pubmed/26734103
http://dx.doi.org/10.3762/bjoc.11.277
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author Martínez, Jose I
Uria, Uxue
Muñiz, Maria
Reyes, Efraím
Carrillo, Luisa
Vicario, Jose L
author_facet Martínez, Jose I
Uria, Uxue
Muñiz, Maria
Reyes, Efraím
Carrillo, Luisa
Vicario, Jose L
author_sort Martínez, Jose I
collection PubMed
description The asymmetric and catalytic Michael reaction between α-nitroesters and nitroalkenes has been studied in the presence of two bifunctional catalysts both containing the same absolute chirality at the carbon backbone. The reaction performed in similar conditions allows us to control the syn or anti selectivity of the Michael adduct obtaining good yields and high enantiocontrol in all cases.
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spelling pubmed-46857932016-01-05 Organocatalytic and enantioselective Michael reaction between α-nitroesters and nitroalkenes. Syn/anti-selectivity control using catalysts with the same absolute backbone chirality Martínez, Jose I Uria, Uxue Muñiz, Maria Reyes, Efraím Carrillo, Luisa Vicario, Jose L Beilstein J Org Chem Full Research Paper The asymmetric and catalytic Michael reaction between α-nitroesters and nitroalkenes has been studied in the presence of two bifunctional catalysts both containing the same absolute chirality at the carbon backbone. The reaction performed in similar conditions allows us to control the syn or anti selectivity of the Michael adduct obtaining good yields and high enantiocontrol in all cases. Beilstein-Institut 2015-12-14 /pmc/articles/PMC4685793/ /pubmed/26734103 http://dx.doi.org/10.3762/bjoc.11.277 Text en Copyright © 2015, Martínez et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Martínez, Jose I
Uria, Uxue
Muñiz, Maria
Reyes, Efraím
Carrillo, Luisa
Vicario, Jose L
Organocatalytic and enantioselective Michael reaction between α-nitroesters and nitroalkenes. Syn/anti-selectivity control using catalysts with the same absolute backbone chirality
title Organocatalytic and enantioselective Michael reaction between α-nitroesters and nitroalkenes. Syn/anti-selectivity control using catalysts with the same absolute backbone chirality
title_full Organocatalytic and enantioselective Michael reaction between α-nitroesters and nitroalkenes. Syn/anti-selectivity control using catalysts with the same absolute backbone chirality
title_fullStr Organocatalytic and enantioselective Michael reaction between α-nitroesters and nitroalkenes. Syn/anti-selectivity control using catalysts with the same absolute backbone chirality
title_full_unstemmed Organocatalytic and enantioselective Michael reaction between α-nitroesters and nitroalkenes. Syn/anti-selectivity control using catalysts with the same absolute backbone chirality
title_short Organocatalytic and enantioselective Michael reaction between α-nitroesters and nitroalkenes. Syn/anti-selectivity control using catalysts with the same absolute backbone chirality
title_sort organocatalytic and enantioselective michael reaction between α-nitroesters and nitroalkenes. syn/anti-selectivity control using catalysts with the same absolute backbone chirality
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685793/
https://www.ncbi.nlm.nih.gov/pubmed/26734103
http://dx.doi.org/10.3762/bjoc.11.277
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