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Inclusion complexes of 2-methoxyestradiol with dimethylated and permethylated β-cyclodextrins: models for cyclodextrin–steroid interaction

The interaction between the potent anticancer agent 2-methoxyestradiol (2ME) and a series of cyclodextrins (CDs) was investigated in the solid state using thermal analysis and X-ray diffraction, while the possibility of enhancing its poor aqueous solubility with CDs was probed by means of equilibriu...

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Detalles Bibliográficos
Autores principales: Caira, Mino R, Bourne, Susan A, Samsodien, Halima, Smith, Vincent J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685897/
https://www.ncbi.nlm.nih.gov/pubmed/26734107
http://dx.doi.org/10.3762/bjoc.11.281