Single-cell chromatin accessibility reveals principles of regulatory variation

Cell-to-cell variation is a universal feature of life that impacts a wide range of biological phenomena, from developmental plasticity(1,2) to tumor heterogeneity(3). While recent advances have improved our ability to document cellular phenotypic variation(4–8) the fundamental mechanisms that genera...

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Detalles Bibliográficos
Autores principales: Buenrostro, Jason D., Wu, Beijing, Litzenburger, Ulrike M., Ruff, Dave, Gonzales, Michael L., Snyder, Michael P., Chang, Howard Y., Greenleaf, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685948/
https://www.ncbi.nlm.nih.gov/pubmed/26083756
http://dx.doi.org/10.1038/nature14590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685948/
https://www.ncbi.nlm.nih.gov/pubmed/26083756
http://dx.doi.org/10.1038/nature14590

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