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Single-cell chromatin accessibility reveals principles of regulatory variation
Cell-to-cell variation is a universal feature of life that impacts a wide range of biological phenomena, from developmental plasticity(1,2) to tumor heterogeneity(3). While recent advances have improved our ability to document cellular phenotypic variation(4–8) the fundamental mechanisms that genera...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685948/ https://www.ncbi.nlm.nih.gov/pubmed/26083756 http://dx.doi.org/10.1038/nature14590 |