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Optogenetics in Mice Performing a Visual Discrimination Task: Measurement and Suppression of Retinal Activation and the Resulting Behavioral Artifact
Optogenetic techniques are used widely to perturb and interrogate neural circuits in behaving animals, but illumination can have additional effects, such as the activation of endogenous opsins in the retina. We found that illumination, delivered deep into the brain via an optical fiber, evoked a beh...
Autores principales: | Danskin, Bethanny, Denman, Daniel, Valley, Matthew, Ollerenshaw, Douglas, Williams, Derric, Groblewski, Peter, Reid, Clay, Olsen, Shawn, Waters, Jack |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686123/ https://www.ncbi.nlm.nih.gov/pubmed/26657323 http://dx.doi.org/10.1371/journal.pone.0144760 |
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