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A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs on Early Embryogenesis

Mammalian fetal development is easily disrupted by exogenous agents, making it essential to test new drug candidates for embryotoxicity and teratogenicity. To standardize the testing of drugs that might be used to treat pregnant women, the U.S. Food and Drug Administration (FDA) formulated special g...

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Detalles Bibliográficos
Autores principales:	Yu, Ruoxing, Miyamura, Norio, Okamoto-Uchida, Yoshimi, Arima, Norie, Ishigami-Yuasa, Mari, Kagechika, Hiroyuki, Nishina, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686177/ https://www.ncbi.nlm.nih.gov/pubmed/26682887 http://dx.doi.org/10.1371/journal.pone.0145286

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