Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa

INTRODUCTION: The objective of this report is to describe the first patient presenting clinical features of trisomy 13 in association with a sacrococcygeal teratoma. CASE PRESENTATION: We present the case of a Congolese female infant born with bilateral cleft lip and palate, hypotelorism, microcepha...

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Detalles Bibliográficos
Autores principales: Lubala, Toni Kasole, Mukuku, Olivier, Shongo, Mick Pongombo, Mutombo, Augustin Mulangu, Lubala, Nina, Luboya, Oscar Numbi, Lukusa-Tshilobo, Prosper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686316/
https://www.ncbi.nlm.nih.gov/pubmed/26715863
http://dx.doi.org/10.2147/IMCRJ.S86098
Descripción
Sumario:INTRODUCTION: The objective of this report is to describe the first patient presenting clinical features of trisomy 13 in association with a sacrococcygeal teratoma. CASE PRESENTATION: We present the case of a Congolese female infant born with bilateral cleft lip and palate, hypotelorism, microcephaly, and capillary hemangioma on her face. She presented with a large sacrococcygeal mass (15.0 cm ×12.0 cm ×5.0 cm) with a cystic consistency and a positive transillumination. CONCLUSION: This observation suggests that overexpression of certain genes on chromosome 13 may lead to tumor formation from remnant cells of Hensen’s node.

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