Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa

INTRODUCTION: The objective of this report is to describe the first patient presenting clinical features of trisomy 13 in association with a sacrococcygeal teratoma. CASE PRESENTATION: We present the case of a Congolese female infant born with bilateral cleft lip and palate, hypotelorism, microcepha...

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Autores principales: Lubala, Toni Kasole, Mukuku, Olivier, Shongo, Mick Pongombo, Mutombo, Augustin Mulangu, Lubala, Nina, Luboya, Oscar Numbi, Lukusa-Tshilobo, Prosper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686316/
https://www.ncbi.nlm.nih.gov/pubmed/26715863
http://dx.doi.org/10.2147/IMCRJ.S86098
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author Lubala, Toni Kasole
Mukuku, Olivier
Shongo, Mick Pongombo
Mutombo, Augustin Mulangu
Lubala, Nina
Luboya, Oscar Numbi
Lukusa-Tshilobo, Prosper
author_facet Lubala, Toni Kasole
Mukuku, Olivier
Shongo, Mick Pongombo
Mutombo, Augustin Mulangu
Lubala, Nina
Luboya, Oscar Numbi
Lukusa-Tshilobo, Prosper
author_sort Lubala, Toni Kasole
collection PubMed
description INTRODUCTION: The objective of this report is to describe the first patient presenting clinical features of trisomy 13 in association with a sacrococcygeal teratoma. CASE PRESENTATION: We present the case of a Congolese female infant born with bilateral cleft lip and palate, hypotelorism, microcephaly, and capillary hemangioma on her face. She presented with a large sacrococcygeal mass (15.0 cm ×12.0 cm ×5.0 cm) with a cystic consistency and a positive transillumination. CONCLUSION: This observation suggests that overexpression of certain genes on chromosome 13 may lead to tumor formation from remnant cells of Hensen’s node.
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spelling pubmed-46863162015-12-29 Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa Lubala, Toni Kasole Mukuku, Olivier Shongo, Mick Pongombo Mutombo, Augustin Mulangu Lubala, Nina Luboya, Oscar Numbi Lukusa-Tshilobo, Prosper Int Med Case Rep J Case Report INTRODUCTION: The objective of this report is to describe the first patient presenting clinical features of trisomy 13 in association with a sacrococcygeal teratoma. CASE PRESENTATION: We present the case of a Congolese female infant born with bilateral cleft lip and palate, hypotelorism, microcephaly, and capillary hemangioma on her face. She presented with a large sacrococcygeal mass (15.0 cm ×12.0 cm ×5.0 cm) with a cystic consistency and a positive transillumination. CONCLUSION: This observation suggests that overexpression of certain genes on chromosome 13 may lead to tumor formation from remnant cells of Hensen’s node. Dove Medical Press 2015-12-11 /pmc/articles/PMC4686316/ /pubmed/26715863 http://dx.doi.org/10.2147/IMCRJ.S86098 Text en © 2015 Lubala et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Lubala, Toni Kasole
Mukuku, Olivier
Shongo, Mick Pongombo
Mutombo, Augustin Mulangu
Lubala, Nina
Luboya, Oscar Numbi
Lukusa-Tshilobo, Prosper
Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa
title Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa
title_full Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa
title_fullStr Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa
title_full_unstemmed Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa
title_short Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa
title_sort sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from central africa
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686316/
https://www.ncbi.nlm.nih.gov/pubmed/26715863
http://dx.doi.org/10.2147/IMCRJ.S86098
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