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A toxic organic solvent-free technology for the preparation of PEGylated paclitaxel nanosuspension based on human serum albumin for effective cancer therapy

Clinically, paclitaxel (PTX) is one of most commonly prescribed therapies against a wide range of solid neoplasms. Despite its success, the clinical applicability of PTX (Taxol(®)) is severely hampered by systemic toxicities induced by Cremophor EL. While attempts to bypass the need for Cremophor EL...

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Detalles Bibliográficos
Autores principales: Yin, Tingjie, Dong, Lihui, Cui, Bei, Wang, Lei, Yin, Lifang, Zhou, Jianping, Huo, Meirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686322/
https://www.ncbi.nlm.nih.gov/pubmed/26715846
http://dx.doi.org/10.2147/IJN.S92697