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A toxic organic solvent-free technology for the preparation of PEGylated paclitaxel nanosuspension based on human serum albumin for effective cancer therapy
Clinically, paclitaxel (PTX) is one of most commonly prescribed therapies against a wide range of solid neoplasms. Despite its success, the clinical applicability of PTX (Taxol(®)) is severely hampered by systemic toxicities induced by Cremophor EL. While attempts to bypass the need for Cremophor EL...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686322/ https://www.ncbi.nlm.nih.gov/pubmed/26715846 http://dx.doi.org/10.2147/IJN.S92697 |