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Role of tumour necrosis factor gene polymorphisms (-308 and -238) in breast cancer susceptibility and severity

INTRODUCTION: Genetic polymorphisms in the promoter region of the tumour necrosis factor (TNF) gene can regulate gene expression and have been associated with inflammatory and malignant conditions. We have investigated two polymorphisms in the promoter of the TNF gene (-308 G>A and -238 G>A) f...

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Detalles Bibliográficos
Autores principales: Azmy, Iman AF, Balasubramanian, Saba P, Wilson, Anthony G, Stephenson, Timothy J, Cox, Angela, Brown, Nicola J, Reed, Malcolm WR
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC468647/
https://www.ncbi.nlm.nih.gov/pubmed/15217507
http://dx.doi.org/10.1186/bcr802