Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic

A key factor in the effectiveness of the seasonal influenza vaccine is its immunological compatibility with the circulating viruses during the season. Here we propose a new bioinformatics approach for analysis of influenza viruses which could be used as an efficient tool for selection of vaccine vir...

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Autores principales: Veljkovic, Veljko, Paessler, Slobodan, Glisic, Sanja, Prljic, Jelena, Perovic, Vladimir R., Veljkovic, Nevena, Scotch, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686605/
https://www.ncbi.nlm.nih.gov/pubmed/26733989
http://dx.doi.org/10.3389/fmicb.2015.01456
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author Veljkovic, Veljko
Paessler, Slobodan
Glisic, Sanja
Prljic, Jelena
Perovic, Vladimir R.
Veljkovic, Nevena
Scotch, Matthew
author_facet Veljkovic, Veljko
Paessler, Slobodan
Glisic, Sanja
Prljic, Jelena
Perovic, Vladimir R.
Veljkovic, Nevena
Scotch, Matthew
author_sort Veljkovic, Veljko
collection PubMed
description A key factor in the effectiveness of the seasonal influenza vaccine is its immunological compatibility with the circulating viruses during the season. Here we propose a new bioinformatics approach for analysis of influenza viruses which could be used as an efficient tool for selection of vaccine viruses, assessment of the effectiveness of seasonal influenza vaccines, and prediction of the epidemic/pandemic potential of novel influenza viruses.
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spelling pubmed-46866052016-01-05 Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic Veljkovic, Veljko Paessler, Slobodan Glisic, Sanja Prljic, Jelena Perovic, Vladimir R. Veljkovic, Nevena Scotch, Matthew Front Microbiol Microbiology A key factor in the effectiveness of the seasonal influenza vaccine is its immunological compatibility with the circulating viruses during the season. Here we propose a new bioinformatics approach for analysis of influenza viruses which could be used as an efficient tool for selection of vaccine viruses, assessment of the effectiveness of seasonal influenza vaccines, and prediction of the epidemic/pandemic potential of novel influenza viruses. Frontiers Media S.A. 2015-12-22 /pmc/articles/PMC4686605/ /pubmed/26733989 http://dx.doi.org/10.3389/fmicb.2015.01456 Text en Copyright © 2015 Veljkovic, Paessler, Glisic, Prljic, Perovic, Veljkovic and Scotch. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Veljkovic, Veljko
Paessler, Slobodan
Glisic, Sanja
Prljic, Jelena
Perovic, Vladimir R.
Veljkovic, Nevena
Scotch, Matthew
Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic
title Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic
title_full Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic
title_fullStr Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic
title_full_unstemmed Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic
title_short Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic
title_sort evolution of 2014/15 h3n2 influenza viruses circulating in us: consequences for vaccine effectiveness and possible new pandemic
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686605/
https://www.ncbi.nlm.nih.gov/pubmed/26733989
http://dx.doi.org/10.3389/fmicb.2015.01456
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