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Stable kinetochore–microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells
During mitosis, duplicated sister chromatids attach to microtubules emanating from opposing sides of the bipolar spindle through large protein complexes called kinetochores. In the absence of stable kinetochore–microtubule attachments, a cell surveillance mechanism known as the spindle assembly chec...
Autores principales: | Tauchman, Eric C., Boehm, Frederick J., DeLuca, Jennifer G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686653/ https://www.ncbi.nlm.nih.gov/pubmed/26620470 http://dx.doi.org/10.1038/ncomms10036 |
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