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Stable kinetochore–microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells

During mitosis, duplicated sister chromatids attach to microtubules emanating from opposing sides of the bipolar spindle through large protein complexes called kinetochores. In the absence of stable kinetochore–microtubule attachments, a cell surveillance mechanism known as the spindle assembly chec...

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Detalles Bibliográficos
Autores principales: Tauchman, Eric C., Boehm, Frederick J., DeLuca, Jennifer G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686653/
https://www.ncbi.nlm.nih.gov/pubmed/26620470
http://dx.doi.org/10.1038/ncomms10036

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