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MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours

Wilms tumour is an embryonal tumour of childhood that closely resembles the developing kidney. Genomic changes responsible for the development of the majority of Wilms tumours remain largely unknown. Here we identify recurrent mutations within Wilms tumours that involve the highly conserved YEATS do...

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Detalles Bibliográficos
Autores principales: Perlman, Elizabeth J., Gadd, Samantha, Arold, Stefan T., Radhakrishnan, Anand, Gerhard, Daniela S., Jennings, Lawrence, Huff, Vicki, Guidry Auvil, Jaime M., Davidsen, Tanja M., Dome, Jeffrey S., Meerzaman, Daoud, Hsu, Chih Hao, Nguyen, Cu, Anderson, James, Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Marra, Marco A., Mullighan, Charles G., Ma, Jing, Wheeler, David A., Hampton, Oliver A., Gastier-Foster, Julie M., Ross, Nicole, Smith, Malcolm A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686660/
https://www.ncbi.nlm.nih.gov/pubmed/26635203
http://dx.doi.org/10.1038/ncomms10013

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