The role of amino acid-induced mammalian target of rapamycin complex 1(mTORC1) signaling in insulin resistance

Mammalian target of rapamycin (mTOR) controls cell growth and metabolism in response to nutrients, energy, and growth factors. Recent findings have placed the lysosome at the core of mTOR complex 1 (mTORC1) regulation by amino acids. Two parallel pathways, Rag GTPase-Ragulator and Vps34-phospholipas...

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Detalles Bibliográficos
Autores principales: Yoon, Mee-Sup, Choi, Cheol Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686696/
https://www.ncbi.nlm.nih.gov/pubmed/27534530
http://dx.doi.org/10.1038/emm.2015.93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686696/
https://www.ncbi.nlm.nih.gov/pubmed/27534530
http://dx.doi.org/10.1038/emm.2015.93

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