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Oral Probiotic VSL#3 Prevents Autoimmune Diabetes by Modulating Microbiota and Promoting Indoleamine 2,3-Dioxygenase-Enriched Tolerogenic Intestinal Environment

The gut microbiota modulates the autoimmune pathogenesis of type 1 diabetes (T1D) via mechanisms that remain largely unknown. The inflammasome components are innate immune sensors that are highly influenced by the gut environment and play pivotal roles in maintaining intestinal immune homeostasis. I...

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Detalles Bibliográficos
Autores principales: Dolpady, Jayashree, Sorini, Chiara, Di Pietro, Caterina, Cosorich, Ilaria, Ferrarese, Roberto, Saita, Diego, Clementi, Massimo, Canducci, Filippo, Falcone, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686713/
https://www.ncbi.nlm.nih.gov/pubmed/26779542
http://dx.doi.org/10.1155/2016/7569431