Cargando…
Oral Probiotic VSL#3 Prevents Autoimmune Diabetes by Modulating Microbiota and Promoting Indoleamine 2,3-Dioxygenase-Enriched Tolerogenic Intestinal Environment
The gut microbiota modulates the autoimmune pathogenesis of type 1 diabetes (T1D) via mechanisms that remain largely unknown. The inflammasome components are innate immune sensors that are highly influenced by the gut environment and play pivotal roles in maintaining intestinal immune homeostasis. I...
Autores principales: | Dolpady, Jayashree, Sorini, Chiara, Di Pietro, Caterina, Cosorich, Ilaria, Ferrarese, Roberto, Saita, Diego, Clementi, Massimo, Canducci, Filippo, Falcone, Marika |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686713/ https://www.ncbi.nlm.nih.gov/pubmed/26779542 http://dx.doi.org/10.1155/2016/7569431 |
Ejemplares similares
-
Increased iNKT17 Cell Frequency in the Intestine of Non-Obese Diabetic Mice Correlates With High Bacterioidales and Low Clostridiales Abundance
por: De Giorgi, Lorena, et al.
Publicado: (2018) -
High frequency of intestinal T(H)17 cells correlates with microbiota alterations and disease activity in multiple sclerosis
por: Cosorich, Ilaria, et al.
Publicado: (2017) -
Loss of gut barrier integrity triggers activation of islet-reactive T cells and autoimmune diabetes
por: Sorini, Chiara, et al.
Publicado: (2019) -
The role of indoleamine 2,3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs
por: Salazar, Fabián, et al.
Publicado: (2017) -
Localization of Indoleamine 2,3-Dioxygenase-1 and Indoleamine 2,3-Dioxygenase-2 at the Human Maternal-Fetal Interface
por: Kudo, Yoshiki, et al.
Publicado: (2020)