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Non-random fragmentation patterns in circulating cell-free DNA reflect epigenetic regulation
BACKGROUND: The assessment of cell-free circulating DNA fragments, also known as a "liquid biopsy" of the patient's plasma, is an important source for the discovery and subsequent non-invasive monitoring of cancer and other pathological conditions. Although the nucleosome-guided fragm...
Autores principales: | Ivanov, Maxim, Baranova, Ancha, Butler, Timothy, Spellman, Paul, Mileyko, Vladislav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686799/ https://www.ncbi.nlm.nih.gov/pubmed/26693644 http://dx.doi.org/10.1186/1471-2164-16-S13-S1 |
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