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Mammalian SRP receptor switches the Sec61 translocase from Sec62 to SRP-dependent translocation

Two distinct pathways deliver secretory proteins to the Sec61 protein translocase in the endoplasmic reticulum membrane. The canonical pathway requires the signal recognition particle (SRP) and its cognate receptor (SR), and targets ribosome-associated proteins to the Sec translocase. The SRP-indepe...

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Detalles Bibliográficos
Autores principales:	Jadhav, Bhalchandra, McKenna, Michael, Johnson, Nicholas, High, Stephen, Sinning, Irmgard, Pool, Martin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686813/ https://www.ncbi.nlm.nih.gov/pubmed/26634806 http://dx.doi.org/10.1038/ncomms10133

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