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Asymmetric ring structure of Vps4 required for ESCRT-III disassembly
The vacuolar protein sorting 4 AAA–ATPase (Vps4) recycles endosomal sorting complexes required for transport (ESCRT-III) polymers from cellular membranes. Here we present a 3.6-Å X-ray structure of ring-shaped Vps4 from Metallosphera sedula (MsVps4), seen as an asymmetric pseudohexamer. Conserved ke...
Autores principales: | Caillat, Christophe, Macheboeuf, Pauline, Wu, Yuanfei, McCarthy, Andrew A., Boeri-Erba, Elisabetta, Effantin, Gregory, Göttlinger, Heinrich G., Weissenhorn, Winfried, Renesto, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686814/ https://www.ncbi.nlm.nih.gov/pubmed/26632262 http://dx.doi.org/10.1038/ncomms9781 |
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