Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution

Patients with chromosome 13q deletion or normal cytogenetics represent the majority of chronic lymphocytic leukaemia (CLL) cases, yet have relatively few driver mutations. To better understand their genomic landscape, here we perform whole-genome sequencing on a cohort of patients enriched with thes...

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Detalles Bibliográficos
Autores principales: Kasar, S., Kim, J., Improgo, R., Tiao, G., Polak, P., Haradhvala, N., Lawrence, M. S., Kiezun, A., Fernandes, S. M., Bahl, S., Sougnez, C., Gabriel, S., Lander, E. S., Kim, H. T., Getz, G., Brown, J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686820/
https://www.ncbi.nlm.nih.gov/pubmed/26638776
http://dx.doi.org/10.1038/ncomms9866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686820/
https://www.ncbi.nlm.nih.gov/pubmed/26638776
http://dx.doi.org/10.1038/ncomms9866

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