Cargando…
Kinetochore–microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint
The spindle assembly checkpoint (SAC) is a genome surveillance mechanism that protects against aneuploidization. Despite profound progress on understanding mechanisms of its activation, it remains unknown what aspect of chromosome–spindle interactions is monitored by the SAC: kinetochore–microtubule...
Autores principales: | Etemad, Banafsheh, Kuijt, Timo E. F., Kops, Geert J. P. L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686852/ https://www.ncbi.nlm.nih.gov/pubmed/26621779 http://dx.doi.org/10.1038/ncomms9987 |
Ejemplares similares
-
Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase
por: Kuijt, Timo E. F., et al.
Publicado: (2014) -
Stable kinetochore–microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells
por: Tauchman, Eric C., et al.
Publicado: (2015) -
Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores
por: Varma, Dileep, et al.
Publicado: (2013) -
Zwint-1 is required for spindle assembly checkpoint function and kinetochore-microtubule attachment during oocyte meiosis
por: Woo Seo, Dong, et al.
Publicado: (2015) -
Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied
por: Brito, Daniela A., et al.
Publicado: (2008)