Structural insight into the mechanism of synergistic autoinhibition of SAD kinases

The SAD/BRSK kinases participate in various important life processes, including neural development, cell cycle and energy metabolism. Like other members of the AMPK family, SAD contains an N-terminal kinase domain followed by the characteristic UBA and KA1 domains. Here we identify a unique autoinhi...

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Detalles Bibliográficos
Autores principales: Wu, Jing-Xiang, Cheng, Yun-Sheng, Wang, Jue, Chen, Lei, Ding, Mei, Wu, Jia-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686854/
https://www.ncbi.nlm.nih.gov/pubmed/26626945
http://dx.doi.org/10.1038/ncomms9953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686854/
https://www.ncbi.nlm.nih.gov/pubmed/26626945
http://dx.doi.org/10.1038/ncomms9953

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