PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis

PICH is a SNF2 family DNA translocase that binds to ultra-fine DNA bridges (UFBs) in mitosis. Numerous roles for PICH have been proposed from protein depletion experiments, but a consensus has failed to emerge. Here, we report that deletion of PICH in avian cells causes chromosome structural abnorma...

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Detalles Bibliográficos
Autores principales: Nielsen, Christian F., Huttner, Diana, Bizard, Anna H., Hirano, Seiki, Li, Tian-Neng, Palmai-Pallag, Timea, Bjerregaard, Victoria A., Liu, Ying, Nigg, Erich A., Wang, Lily Hui-Ching, Hickson, Ian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686863/
https://www.ncbi.nlm.nih.gov/pubmed/26643143
http://dx.doi.org/10.1038/ncomms9962

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