The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids

The epithelial lining of the fallopian tube is of critical importance for human reproduction and has been implicated as a site of origin of high-grade serous ovarian cancer. Here we report on the establishment of long-term, stable 3D organoid cultures from human fallopian tubes, indicative of the pr...

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Detalles Bibliográficos
Autores principales: Kessler, Mirjana, Hoffmann, Karen, Brinkmann, Volker, Thieck, Oliver, Jackisch, Susan, Toelle, Benjamin, Berger, Hilmar, Mollenkopf, Hans-Joachim, Mangler, Mandy, Sehouli, Jalid, Fotopoulou, Christina, Meyer, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686873/
https://www.ncbi.nlm.nih.gov/pubmed/26643275
http://dx.doi.org/10.1038/ncomms9989

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