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Association between maternal obesity and offspring Apgar score or cord pH: a systematic review and meta-analysis

Previous results are inconsistent regarding the association between maternal obesity and Apgar score or cord pH in humans. The aim of this study was to investigate the association between maternal pre-pregnancy and pregnancy body mass index (BMI) and infant Apgar score or cord pH. We conducted a sys...

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Autores principales: Zhu, Tingting, Tang, Jun, Zhao, Fengyan, Qu, Yi, Mu, Dezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686911/
https://www.ncbi.nlm.nih.gov/pubmed/26692415
http://dx.doi.org/10.1038/srep18386
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author Zhu, Tingting
Tang, Jun
Zhao, Fengyan
Qu, Yi
Mu, Dezhi
author_facet Zhu, Tingting
Tang, Jun
Zhao, Fengyan
Qu, Yi
Mu, Dezhi
author_sort Zhu, Tingting
collection PubMed
description Previous results are inconsistent regarding the association between maternal obesity and Apgar score or cord pH in humans. The aim of this study was to investigate the association between maternal pre-pregnancy and pregnancy body mass index (BMI) and infant Apgar score or cord pH. We conducted a systematic review of studies published in English before 20 August 2015 using PubMed, EMBASE, and Cochrane Library. Eleven cohort studies with a total of 2,586,265 participants finally met our inclusion criteria. Pooled results revealed the following factors associated with Apgar score <7 at 5 minutes: overweight (odds ratio [OR] 1.13; 95% confidence interval [CI], 1.08–1.20), obese (OR 1.40; 95% CI, 1.27–1.54), and very obese (OR 1.71; 95% CI, 1.55–1.89). The pooled analysis also revealed that maternal overweight or obesity increased the risk for Apgar score <7 at 1 minute. There was no association between maternal BMI and neonatal cord pH. Thus, this study suggests that maternal overweight and obesity affect baby’s condition immediately after birth in general. More studies are needed to confirm these results and detect the influence of variables across studies.
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spelling pubmed-46869112015-12-31 Association between maternal obesity and offspring Apgar score or cord pH: a systematic review and meta-analysis Zhu, Tingting Tang, Jun Zhao, Fengyan Qu, Yi Mu, Dezhi Sci Rep Article Previous results are inconsistent regarding the association between maternal obesity and Apgar score or cord pH in humans. The aim of this study was to investigate the association between maternal pre-pregnancy and pregnancy body mass index (BMI) and infant Apgar score or cord pH. We conducted a systematic review of studies published in English before 20 August 2015 using PubMed, EMBASE, and Cochrane Library. Eleven cohort studies with a total of 2,586,265 participants finally met our inclusion criteria. Pooled results revealed the following factors associated with Apgar score <7 at 5 minutes: overweight (odds ratio [OR] 1.13; 95% confidence interval [CI], 1.08–1.20), obese (OR 1.40; 95% CI, 1.27–1.54), and very obese (OR 1.71; 95% CI, 1.55–1.89). The pooled analysis also revealed that maternal overweight or obesity increased the risk for Apgar score <7 at 1 minute. There was no association between maternal BMI and neonatal cord pH. Thus, this study suggests that maternal overweight and obesity affect baby’s condition immediately after birth in general. More studies are needed to confirm these results and detect the influence of variables across studies. Nature Publishing Group 2015-12-22 /pmc/articles/PMC4686911/ /pubmed/26692415 http://dx.doi.org/10.1038/srep18386 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Zhu, Tingting
Tang, Jun
Zhao, Fengyan
Qu, Yi
Mu, Dezhi
Association between maternal obesity and offspring Apgar score or cord pH: a systematic review and meta-analysis
title Association between maternal obesity and offspring Apgar score or cord pH: a systematic review and meta-analysis
title_full Association between maternal obesity and offspring Apgar score or cord pH: a systematic review and meta-analysis
title_fullStr Association between maternal obesity and offspring Apgar score or cord pH: a systematic review and meta-analysis
title_full_unstemmed Association between maternal obesity and offspring Apgar score or cord pH: a systematic review and meta-analysis
title_short Association between maternal obesity and offspring Apgar score or cord pH: a systematic review and meta-analysis
title_sort association between maternal obesity and offspring apgar score or cord ph: a systematic review and meta-analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686911/
https://www.ncbi.nlm.nih.gov/pubmed/26692415
http://dx.doi.org/10.1038/srep18386
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