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Comparative Proteomic Profiling of Ehrlichia ruminantium Pathogenic Strain and Its High-Passaged Attenuated Strain Reveals Virulence and Attenuation-Associated Proteins

The obligate intracellular bacterium Ehrlichia ruminantium (ER) causes heartwater, a fatal tick-borne disease in livestock. In the field, ER strains present different levels of virulence, limiting vaccine efficacy, for which the molecular basis remains unknown. Moreover, there are no genetic tools c...

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Detalles Bibliográficos
Autores principales:	Marcelino, Isabel, Ventosa, Miguel, Pires, Elisabete, Müller, Markus, Lisacek, Frédérique, Lefrançois, Thierry, Vachiery, Nathalie, Coelho, Ana Varela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686967/ https://www.ncbi.nlm.nih.gov/pubmed/26691135 http://dx.doi.org/10.1371/journal.pone.0145328

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