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Differential Toll-Like Receptor-Signalling of Burkholderia pseudomallei Lipopolysaccharide in Murine and Human Models

The Gram-negative bacterium Burkholderia pseudomallei causes melioidosis and is a CDC category B bioterrorism agent. Toll-like receptor (TLR)-2 impairs host defense during pulmonary B.pseudomallei infection while TLR4 only has limited impact. We investigated the role of TLRs in B.pseudomallei-lipopo...

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Detalles Bibliográficos
Autores principales:	Weehuizen, Tassili A. F., Prior, Joann L., van der Vaart, Thomas W., Ngugi, Sarah A., Nepogodiev, Sergey A., Field, Robert A., Kager, Liesbeth M., van ‘t Veer, Cornelis, de Vos, Alex F., Wiersinga, W. Joost
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687033/ https://www.ncbi.nlm.nih.gov/pubmed/26689559 http://dx.doi.org/10.1371/journal.pone.0145397

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