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Aeroallergen Der p 2 induces apoptosis of bronchial epithelial BEAS-2B cells via activation of both intrinsic and extrinsic pathway
BACKGROUND: Excessive apoptosis of airway epithelium is reported to induce airway remodeling and inhibited airway epithelium repair is highly associated with development of asthma and chronic obstructive pulmonary disease. Der p 2 is a major allergen derived from Dermatophagoides pteronyssinus and c...
Autores principales: | Lin, Chun-Hsiang, Hong, Yu-Chuan, Kao, Shao-Hsuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687151/ https://www.ncbi.nlm.nih.gov/pubmed/26697166 http://dx.doi.org/10.1186/s13578-015-0063-5 |
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