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Metastatic adenocarcinoma of the cervix presenting as a choroidal mass: A case report and review of literature of cervical metastases to the eye

Cervical cancer is the most common cancer among females in India. Cervical cancer usually spreads by local extension and through the lymphatic drainage to the lymph nodes. Hematogenous spread, the mechanism responsible for distant metastases, is rarely seen in cervical malignancies. In this communic...

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Autores principales: Nair, Akshay Gopinathan, Asnani, Haresh T, Mehta, Vinod C, Mehta, Siddharth V, Pathak, Rima S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687196/
https://www.ncbi.nlm.nih.gov/pubmed/26576527
http://dx.doi.org/10.4103/0301-4738.169792
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author Nair, Akshay Gopinathan
Asnani, Haresh T
Mehta, Vinod C
Mehta, Siddharth V
Pathak, Rima S
author_facet Nair, Akshay Gopinathan
Asnani, Haresh T
Mehta, Vinod C
Mehta, Siddharth V
Pathak, Rima S
author_sort Nair, Akshay Gopinathan
collection PubMed
description Cervical cancer is the most common cancer among females in India. Cervical cancer usually spreads by local extension and through the lymphatic drainage to the lymph nodes. Hematogenous spread, the mechanism responsible for distant metastases, is rarely seen in cervical malignancies. In this communication, we report a case of a 45-year-old woman who presented with unilateral decrease in vision of 3 months duration. She was found to have a serous retinal detachment with underlying diffuse, subretinal yellowish-cream colored infiltrates in the right eye, suspicious of choroidal metastases. Systemic evaluation showed disseminated systemic metastases arising from a primary adenocarcinoma of the cervix. In this communication, we review all the documented cases of metastases to the eye and adnexa arising from cervical cancer and their clinical characteristics. Unilateral choroidal metastasis arising from an adenocarcinoma of the cervix is extremely rare with only one previous documented case. Although uncommon, choroidal metastasis may be the presenting feature of primary cervical malignancy. Furthermore, cervical malignancy must be ruled out in women who present with orbital or choroidal metastases arising from unknown primary.
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spelling pubmed-46871962016-01-04 Metastatic adenocarcinoma of the cervix presenting as a choroidal mass: A case report and review of literature of cervical metastases to the eye Nair, Akshay Gopinathan Asnani, Haresh T Mehta, Vinod C Mehta, Siddharth V Pathak, Rima S Indian J Ophthalmol Brief Communications Cervical cancer is the most common cancer among females in India. Cervical cancer usually spreads by local extension and through the lymphatic drainage to the lymph nodes. Hematogenous spread, the mechanism responsible for distant metastases, is rarely seen in cervical malignancies. In this communication, we report a case of a 45-year-old woman who presented with unilateral decrease in vision of 3 months duration. She was found to have a serous retinal detachment with underlying diffuse, subretinal yellowish-cream colored infiltrates in the right eye, suspicious of choroidal metastases. Systemic evaluation showed disseminated systemic metastases arising from a primary adenocarcinoma of the cervix. In this communication, we review all the documented cases of metastases to the eye and adnexa arising from cervical cancer and their clinical characteristics. Unilateral choroidal metastasis arising from an adenocarcinoma of the cervix is extremely rare with only one previous documented case. Although uncommon, choroidal metastasis may be the presenting feature of primary cervical malignancy. Furthermore, cervical malignancy must be ruled out in women who present with orbital or choroidal metastases arising from unknown primary. Medknow Publications & Media Pvt Ltd 2015-08 /pmc/articles/PMC4687196/ /pubmed/26576527 http://dx.doi.org/10.4103/0301-4738.169792 Text en Copyright: © 2015 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Brief Communications
Nair, Akshay Gopinathan
Asnani, Haresh T
Mehta, Vinod C
Mehta, Siddharth V
Pathak, Rima S
Metastatic adenocarcinoma of the cervix presenting as a choroidal mass: A case report and review of literature of cervical metastases to the eye
title Metastatic adenocarcinoma of the cervix presenting as a choroidal mass: A case report and review of literature of cervical metastases to the eye
title_full Metastatic adenocarcinoma of the cervix presenting as a choroidal mass: A case report and review of literature of cervical metastases to the eye
title_fullStr Metastatic adenocarcinoma of the cervix presenting as a choroidal mass: A case report and review of literature of cervical metastases to the eye
title_full_unstemmed Metastatic adenocarcinoma of the cervix presenting as a choroidal mass: A case report and review of literature of cervical metastases to the eye
title_short Metastatic adenocarcinoma of the cervix presenting as a choroidal mass: A case report and review of literature of cervical metastases to the eye
title_sort metastatic adenocarcinoma of the cervix presenting as a choroidal mass: a case report and review of literature of cervical metastases to the eye
topic Brief Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687196/
https://www.ncbi.nlm.nih.gov/pubmed/26576527
http://dx.doi.org/10.4103/0301-4738.169792
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