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Genome-wide transcriptome profiling reveals functional networks involving the Plasmodium falciparum drug resistance transporters PfCRT and PfMDR1

BACKGROUND: The acquisition of multidrug resistance by Plasmodium falciparum underscores the need to understand the underlying molecular mechanisms so as to counter their impact on malaria control. For the many antimalarials whose mode of action relates to inhibition of heme detoxification inside in...

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Detalles Bibliográficos
Autores principales:	Adjalley, Sophie H., Scanfeld, Daniel, Kozlowski, Elyse, Llinás, Manuel, Fidock, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687325/ https://www.ncbi.nlm.nih.gov/pubmed/26689807 http://dx.doi.org/10.1186/s12864-015-2320-8

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